Urosphere

publications

TitleReferenceshf:tax:categoryhf:tax:publiyear
A new tumorgraft panel to accelerate precision medicine in prostate cancer

Béraud C. et al., 2023. Frontiers in Oncology, 13

OPENoncology publications2023
Experimental in vivo model to evaluate the impact of Cernitin™ on pain response on induced chronic bladder inflammation

Augé C. et al., 2022. Scandinavian Journal of Urology, 56 (4)

OPENpublications urology2022
Integrated molecular and pharmacological characterization of patient derived xenografts from bladder and ureteral cancers identifies new potential therapies

Lang H. et al., 2022. Frontiers in Oncology, 12

OPENoncology publications2022
Impact of Cernitin™ on induced chronic prostatitis in animal model for understanding management of lower urinary tract symptoms

Chabot S. et al., 2021. Phytomedicine Plus, 1(4)

OPENandrology publications2021
Pain Management in a Model of Interstitial Cystitis/Bladder Pain Syndrome by a Vaccinal Strategy

Augé C. et al., 2021. Frontiers in Pain Research, 2:642706

OPENpublications urology2021
Recurrent activating mutations of PPAR γ associated with luminal bladder tumors

Rochel N. et al., 2019. Nature Communications, 10(1):253.

OPENnon-classe oncology publications2019
An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers

Mahe M. et al., 2018. EMBO Molecular Medicine, 10(4):e8163

OPENoncology publications2018
Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma

Lang H. et al., 2016. Oncotarget, 7:59336-59359

OPENoncology publications2016
Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats

Augé C. et al., 2020. Frontiers in Pharmacology. 11:1305

OPENpublications urology2020
Mobilization of CD4+ T lymphocytes in inflamed mucosa reduces pain in colitis mice: toward a vaccinal strategy to alleviate inflammatory visceral pain

Basso L. et al., 2018. Pain, 159(2):331-341

OPENgatsroenterology publications2018
Development of a near infrared protein nanoprobe targeting Thomsen-Friedenreich antigen for intraoperative detection of submillimeter nodules in an ovarian peritoneal carcinomatosis mouse model

Coustets M. et al. , 2020. Biomaterials, volume 241

OPENoncology publications2020
Estrogen Receptors and Endometriosis

Chantalat E. et al., 2020. International Journal of Molecular Sciences, 21(8):2815

OPENgynecology publications2020
Characterization of human colon organoids from Inflammatory Bowel Disease patients

D’Aldebert E. et al., 2020. Frontiers in Cell and Developmental Biology, volume 8:363

OPENgatsroenterology publications2020
Protease-activated receptor-4 (PAR 4): a role as inhibitor of visceral pain and hypersensitivity

Augé C. et al., 2009. Neurogastroenterology & motility, 21(11):1189

OPENgatsroenterology publications2009
Effects of litoxetine on urethral pressure and detrusor overactivity in anesthetized female rats.

Méen M. et al.,. 2017. 32nd Annual EAU Congress

OPENpublications urology2017
Effects of litoxetine on acetic acid-induced detrusor overactivity and striated anal sphincter functions in rabbits: comparison with duloxetine.

Pérez-Martinez F. et al., . 2017, 32nd Annual EAU Congress

OPENpublications urology2017
OBE022, an Oral and Selective Prostaglandin F2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor

Polh O. et al., 2018. Journal of Pharmacology and Experimental Therapeutics, 366 (2) 349-364

OPENgynecology publications2018
Cultures d’organoïdes de vessie humaine : un nouveau modèle d’étude.

Tostivint V. et al.,  2016. Progrès en Urologie, 26(13):765-766.

OPENpublications urology2016
FAK (Focal Adhesion Kinase) mRNA variants in colorectal cancer.

Devaud C. et al., 2019. International Journal of Cancer, 145(2): 494–502.

OPENoncology publications2019
Netupitant, a Potent and Highly Selective NK1 Receptor Antagonist, Alleviates Acetic Acid-Induced Bladder Overactivity in Anesthetized Guinea-Pigs.

Palea S, et al., 2016, Frontiers in Pharmacology, 7:234.

OPENpublications urology2016
Effects of JNK inhibitor on puromycin aminonucleoside-induced nephropathy in rats

Alfarano C. et al., 2016. 53rd ERA-EDTA Congress.

OPENnephrology publications2016
Effect of JNK inhibitor in a rat model of renal ischemia-reperfusion injury

Alfarano C. et al., 2016. 53rd ERA-EDTA Congress.

OPENnephrology publications2016
Immunotherapy to treat Bladder Painful Syndrome

Augé C. et al., 2016. 31st Annual EAU Congress.

OPENpublications urology2016
Development and validation of clinically-relevant chronic model of IC/BPS

Chabot C. et al., 2016. 31st Annual EAU Congress.

OPENpublications urology2016
Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

Legrier ME. et al., 2016. British Journal of Cancer, 114:177-187.

OPENoncology publications2016
Differences in the contractility of human isolated prostatic urethra to oxytocin and norepinephrine in benign prostatic hyperplasia: potential role of oxytocin in BPH.

McCallum S. et al., 2015. The Journal of Urology. 193:e356,

OPENandrology publications urology2015
Effect of tadalafil in a rat model of renal ischemia-reperfusion injury

Alfarano C. et al., 2014. 51st ERA-EDTA CONGRESS

OPENnephrology publications2014
Comparison of the effects of ß3-adrenoceptor agonism on urinary bladder function in conscious, anesthetized, and spinal cord injured rats.

Beauval JB. et al., 2014. Neurourology Urodynamics. 34(6):578-85

OPENpublications urology2014
Targeted electro-delivery of oligonucleotides for RNA interference: siRNA and antimiR.

Chabot S. et al., 2014. Advanced Drug Delivery Reviews, 81:161-168 

OPENoncology publications2014
Modulation of nerve-evoked contractions by ß3-adrenoceptor agonism in human and rat isolated urinary bladder.

Rouget C. et al., 2014. Pharmacology Research. 80:14-20

OPENpublications urology2014
ADX71441, a novel, potent and selective positive allosteric modulator of the GABA(B) receptor, shows efficacy in rodent models of overactive bladder.

Kalinichev M. et al., 2014. British Journal of Pharmacology. 171:995-1006

OPENpublications urology2014
The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus.

Javid FA. et al., 2014. European Journal of Pharmacology. 723:489-93,

OPENpublications urology2014
Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder.

Augé C. et al., 2013. European Journal of Pharmacology. 707:32-40, 2013

OPENpublications urology2013
Effects of p-Da1a a peptidic a(1) (A) -adrenoceptor antagonist in human isolated prostatic adenoma and anaesthetized rats.

Palea S. et al. 2013. British Journal of Pharmacology. 168:618-3

OPENandrology publications urology2013
Fenoterol functionally activates the ß(3)-adrenoceptor in human urinary bladder, comparison with rat and mouse: implications for drug discovery

Palea S. et al., 2012. European Journal of Pharmacology. 690: 202-206

OPENpublications urology2012
Nociceptive measures in chronic prostatitis: a model of inflammation-induced pelvic pain in rats.

Augé C. et al., 2012. 14th World Congress on Pain

OPENpublications urology2012
Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the ß (3)-adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction.

Gillespie JI. et al., 2012. BJU International. 110:132-42

OPENpublications urology2012
Oxytocin produces contraction of human isolated prostate, an effect blocked by the novel and selective oxytocin receptor antagonist GSK557296: potential role in benign prostatic hyperplasia.

McCallum S. et al., 2012. Annual AUA Congress

OPENpublications urology2012
Effects of a selective beta3 adrenergic agonist (CL-316,243) on cystometric parameters in conscious normal and spinal cord injured female rat.

Beauval JB. et al., 2012. Annual AUA Congress

OPENpublications urology2012
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats.

Alfarano C. et al., 2012. Cell Transplantation, 21(9):2009-19

OPENnephrology publications2012
G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors.

Maïga A. et al., 2012. Toxicon 59:487-96

OPENpublications urology2012
Drug delivery by electropulsation: Recent developments in oncology.

Teissié J. et al., 2012. International Journal of Pharmaceutics, 423:3-6

OPENoncology publications2012
Electrotransfer of RNAi-based oligonucleotides for oncology.

Chabot S. et al., 2011. Anticancer Research, 31:4083-9

OPENoncology publications2011
Pharmacological modulation of urinary bladder inflammation in a rat model of cyclophosphamide induced acute bladder pain.

Augé. C. et al., 2011.10th World Congress on Pain

OPENpublications urology2011
Evaluation of pro-resolving mediators during urinary bladder inflammation: effect of aspirin, ibuprofen and morphine.

Dubourdeau M. et al., 2011. 10th World Congress on Pain

OPENpublications urology2011
A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor.

Chabot S. et al., 2011. Journal of Experimental Medicine, 208:973-86

OPENoncology publications2011
The halothane-anesthetized rabbit: A new experimental model to test the effects of monoamine uptake inhibitors on the lower urinary tract function.

Pérez-Martínez FC. et al., 2011. Urologia Internationalis, 86:210-219

OPENpublications urology2011
Involvement of both beta2- and beta3-adrenoceptors in the inhibition of neurogenic contractions of mouse isolated urinary bladder

Rouget C. et al., 2010. 16th World Congress of Basic and Clinical Pharmacology

OPENpublications urology2010
Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor

Quinton L,. et al., 2010. British Journal of Pharmacology, 159:316-325

OPENpublications urology2010
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization.

Buron N. et al., 2010. PLoS One, 5:e9924

OPENoncology publications2010
ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target.

Bikeye SN. et al., 2010. Cancer Cell International, 10:1

OPENoncology publications2010
A Flavivirus protein M-derived Peptide Directly Permeabilizes Mitochondrial Membranes, Triggers Cell Death and Reduces Human Tumor Growth in Nude Mice

Brabant M. et al., 2009. Apoptosis, 14:1190-203

OPENoncology publications2009
Increase in arachidonic acid metabolites in the urine of female rats with cyclophosphamide-induced cystitis.

Lluel P. et al., 2009. 39th Annual Meeting of the International Continence Society (ICS) 

OPENpublications urology2009
Involvement of ß3-adrenoceptors in mouse urinary bladder function: role in detrusor muscle relaxation and micturition reflex.

Deba A. et al., 2009. European Journal of Pharmacology 618:76-83

OPENpublications urology2009
Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: a possible model for intraoperative floppy iris syndrome (IFIS).

Palea S. et al., 2008. Journal of Cataract & Refractive Surgery. 34:489-496

OPENpublications urology2008
Soluble HLA-G and control of angiogenesis.

Le Bouteiller P. et al., 2007. Journal of Reproductive Immunology, 76:17-22

OPENoncology publications2007
Targeted Vpr-derived Peptides Reach Mitochondria to Induce Apoptosis of αVβ3-Expressing Endothelial Cells

Borgne-Sanchez A. et al., 2007. Cell Death and Differentiation, 14:422-35.

OPENoncology publications2007
Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells.

Fons P. et al., 2006. Blood, 108:2608-15

OPENoncology publications2006
Involvement of 5-HT7 receptors in the 5-HT excitatory effects on the rat urinary bladder.

Palea S. et al., 2004. British Journal of Urology, 94:1125-31.

OPENpublications urology2004
Increased adrenergic contractility and decreased mRNA expression of NOS III in aging rat urinary bladders.

Lluel P. et al., 2003. Fundamental & clinical Pharmacology. 17:633-41

OPENpublications urology2003
Comparison of the relaxant effects of alfuzosin, phentolamine and sildenafil on rabbit isolated corpus cavernosum

Barras M and Palea S., 2003. BJU International, 91:873-7

OPENpublications urology2003
Age-related changes in urethro-vesical coordination in male rats: relationship with bladder instability.

Lluel P. et al.,  2003. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 284:1287-1295

OPENpublications urology2003
Cholinergic and purinergic contribution to the micturition reflex in conscious rats with long-term bladder outlet obstruction.

Lluel P. et al., 2002. Neurourology and Urodynamics, 21:142-153

OPENpublications urology2002
Involvement of hypogastric and pelvic nerves for conveying cystitis induced nociception in conscious rats.

Meen M. et al., 2001. Journal of Urology. 166:318-22.

OPENpublications urology2001
Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain.

Boucher M. et al., 2000. Journal of  Urology, 164:203-8

OPENpublications urology2000
Functional and morphological modifications of the urinary bladder in aging female rats.

Lluel P. et al., 2000. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 278:964-72

OPENpublications urology2000
Effects of intracolonic opioid receptor agonists on polymodal pelvic nerve afferent fibers in the rat.

Su X. et al., 2000. Journal of Neurophysiology, 83:963-70

OPENgatsroenterology publications2000
Pharmacological and urodynamic changes in rat urinary bladder function after multiple pregnancies.

Grandadam F. et al., 1999. BJU International, 84:861-6

OPENpublications urology1999
Role of neurokinin 3 receptors on responses to colorectal distention in the rat: electrophysiological and behavioral studies.

Julia V. et al., 1999. Gastroenterology, 116:1124-31

OPENgatsroenterology publications1999
Involvement of spinal NK1 and opioids receptors in modulating the inhibitory effects of capsaicin on micturition reflex in the acute spinalized guinea pigs.

Palea S. and Pietra C. 1999. Journal of Urology, 161: 998-1005

OPENpublications urology1999
Role of vasoactive intestinal polypeptide in the adaptation of intestinal smooth muscle cells to mechanical distension.

Rekik M. et al., 1998. Journal of Pharmacology and Experimental Therapeutics, 287:832-8.

OPENgatsroenterology publications1998
Experimental bladder instability following bladder outlet obstruction in the female rat.

Lluel P. et al., 1998. Journal of Urology, 160:2253-2257.

OPENpublications urology1998
Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrations.

Martin DJ. et al., 1998. Life Sciences, 63:169-176

OPENpublications urology1998
The adrenergic, cholinergic and NANC nerve-mediated contractions of the female rabbit bladder neck and proximal, medial and distal urethra.

Deplanne V. et al., 1998. British Journal of Pharmacology, 123: 1517-1524

OPENpublications urology1998
The effect of ovariectomy on the contractile response of the rat isolated detrusor muscle and urethra.

Palea S. and Angel I., 1997. Life Sciences, …

OPENpublications urology1997
The calcitonin gene-related peptide activates both cAMP and NO pathways to induce relaxation of circular smooth muscle cells of guinea-pig ileum.

Rekik M. et al., 1997. Peptides, 18:1517-22.

OPENgatsroenterology publications1997
Comparative alpha-1 adrenoceptor subtype selectivity and functional uroselectivity of alpha-1 adrenoceptor antagonists.

Martin DJ. et al., 1997. Journal of Pharmacology and Experimental Therapeutics, 282:228-235.

OPENpublications urology1997
Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: role of CGRP.

Julia V and Buéno L. 1997. American Journal of Physiology-Gastrointestinal and Liver Physiology,  272:G141-6.

OPENgatsroenterology publications1997
VIP-induced relaxation of guinea-pig intestinal smooth muscle cells: sequential involvement of cyclic AMP and nitric oxide.

Rekik M. et al., 1996. British Journal of Pharmacology, 118:477-84.

OPENgatsroenterology publications1996
Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate.

Palea S. et al., 1996. Journal of Pharmacology and Experimental Therapeutics , 277 (2) 700-705.

OPENpublications urology1996
Failure of the putative neuropeptide Y antagonists, benextramine and PYX-2, to inhibit Y2 receptors in rat isolated prostatic vas deferens.

Palea S. et al., 1995. British journal of pharmacology, 116:2401-2406.

OPENandrology publications urology1995
Influence of bradykinin in gastrointestinal disorders and visceral pain induced by acute or chronic inflammation in rats.

Julia V. et al., 1995. Digestive Diseases and Sciences, 40:1913-21

OPENgatsroenterology publications1995
Discrimination by benextramine between the NPY-Y1 receptor subtypes present in rabbit isolated vas deferens and saphenous vein.

Palea S. et al., 1995. British Journal of  Pharmacology. 115:3-10.

OPENpublications urology1995
Evidence for the presence of both pre- and postjunctional P2-purinoceptor subtypes in human isolated urinary bladder.

Palea S. et al., 1995. British Journal of Pharmacology, 114:35-40

OPENpublications urology1995
Parathyroid hormone (PTH) and PTH-related peptide induce relaxation of smooth muscle cells from guinea pig ileum: interaction with vasoactive intestinal peptide receptors.

Botella A. et al., 1994. Endocrinology, 135:2160-7.

OPENgatsroenterology publications1994
A further analysis of the contraction induced by activation of cholecystokinin A receptors in guinea pig isolated ileum longitudinal muscle-myenteric plexus.

Corsi M. et al., 1994. Journal of Pharmacology and Experimental Therapeutics, 270:734-740.

OPENpublications urology1994
Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats.

Julia V. et al., 1994. Gastroenterology, 107:94-102

OPENgatsroenterology publications1994
Influence of 5-HT3 receptor antagonists in visceromotor and nociceptive responses to rectal distension before and during experimental colitis in rats.

Morteau O. et al., 1994. Fundamental & Clinical Pharmacology, 8:553-62.

OPENgatsroenterology publications1994
ADP beta-S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y.

Palea S. et al., 1994. Journal of Pharmacology and Experimental Therapeutics, 269:193-197

OPENpublications urology1994
Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis.

Palea S. et al., 1993. Journal of Urology, 150:2007-2012

OPENpublications urology1993
Further studies on the effects of selective neurokinin agonists upon the activation of micturition reflex in rats. Evidence for a dual NK1 receptor mediated excitatory and inhibitory activity.

Palea S. et al., 1993. Neuropeptides. 24:285-291

OPENpublications urology1993