- Preclinical proof of concept in target tissue
- Direct relevance to humans
- Provides valuable information early in the drug discovery process by supplying early indications on the efficacy and safety of investigational compounds
Human tissue services
Human urogenital tissue
Advantages of functional pharmacology assays using human tissue
Tissue supply / Ethics
- UROsphere obtains donated human tissues in a strictly ethical manner through a secure and dedicated network of French hospitals
- UROsphere complies with bioethical French legislation (law n° 2004-800) and the public health code (decree n° 97-928)
- The company has ethical approval of it's research by French authorities (CNREEA)
A highly qualified and dedicated team
- Scientists specifically trained and dedicated to experiments using human tissue
- Internal standard operating procedure for human tissue experimentation
- Vast experience using human isolated tissues
Scientific publications
- Palea S et al, J Pharmacol Exp Ther 277: 700-5, 1996
- Palea S et al, Br J Pharmacol 124: 865-72, 1998
- Palea S et al, Neurourol Urodyn 19: 431-33, 1998
- Rouget C et al, Br J Pharmacol 141: 831-41, 2004
- Rouget C et al, J Clin Endocrinol Metab 90: 1644-50, 2005
- Palea S et al, Eur Urol 5 (Sup 2), 39, 2006
- Rouget C et al, Reprod 74: 209-16, 2006
Offering by pathologies