UROSPHERE

services

Urosphere provides a range of services based on our innovative experimental model.

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Evaluation of contraction or relaxation of human isolated tissuesDownload PDFurologyin-vitro
Acute cystitis induced by cyclophosphamide in miceDownload PDFbladder-painful-syndrome-bps-interstitial-cystitis urologyin-vivo
Chronic cystitis induced by cyclophosphamideDownload PDFbladder-painful-syndrome-bps-interstitial-cystitis urologyin-vivo
Acute cystitis induced by cyclophosphamide in ratsDownload PDFbladder-painful-syndrome-bps-interstitial-cystitis urologyin-vivo
Evaluation of contraction or relaxation of animal isolated tissuesDownload PDFurologyin-vitro
Spinal cord injury-induced detrusor overactivityDownload PDFneurogenic-bladder urologyin-vivo
Urethral pressure measurementsDownload PDFstress-and-mixed-incontinence urologyin-vivo
Simultaneous recording of intraurethral and intravesical pressuresDownload PDFstress-and-mixed-incontinence urologyin-vivo
PS/LPS induced bladder inflammationDownload PDFbladder-painful-syndrome-bps-interstitial-cystitis urologyin-vivo
PS/KCl induced bladder inflammationDownload PDFbladder-painful-syndrome-bps-interstitial-cystitis urologyin-vivo
External urethral sphincter (EUS) electromyographyDownload PDFstress-and-mixed-incontinence urologyin-vivo
Diabetic bladder dysfunction modelDownload PDFbladder-function-and-overactive-bladder-oab urologyin-vivo
Isovolumetric bladder modelDownload PDFbladder-function-and-overactive-bladder-oab urologyin-vivo
Bladder Outlet Obstruction (BOO) induced bladder hyperactivity in ratsDownload PDFbladder-function-and-overactive-bladder-oab urologyin-vivo
Acetic acid-induced hyperactive bladderDownload PDFbladder-function-and-overactive-bladder-oab urologyin-vivo
Chronic pelvic pain and inflammation induced by carrageenanDownload PDFandrology prostatitis prostatitis-andrology urologyin-vivo
Chronic prostate hyperplasia and inflammation induced by sulpirideDownload PDFbenign-prostatic-hyperplasia-bph urologyin-vivo
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Unilateral Ureteral Obstruction (UUO)Download PDFnephrology obstructive-nephropathyin-vivo
A model of chronic kidney disease: NIRC (Nephrectomy + Ischemia Reperfusion + Cyclosporin)Download PDFchronic-kidney-injury nephrologyin-vivo
Puromycine aminonucleoside (PAN)-induced nephropathyDownload PDFfocal-segmental-glomerulosclerosis nephrology obstructive-nephropathyin-vivo
Adriamycin (ADR)-induced nephropathyDownload PDFfocal-segmental-glomerulosclerosis nephrology obstructive-nephropathyin-vivo
Unilateral nephrectomy and Ischemia reperfusion injury (NIR)Download PDFacute-kidney-injury-aki nephrologyin-vivo
Bilateral kidney ischemia / reperfusion injuryDownload PDFacute-kidney-injury-aki nephrologyin-vivo
Diabetic nephropathy db/db miceDownload PDFdiabetic-nephropathy nephrologyin-vivo
Diabetic nephropathy STZ ratDownload PDFdiabetic-nephropathy nephrologyin-vivo
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Cancer cell line tumor xenograft modelsDownload PDFbladder-cancer-oncology breast-cancer colon-cancer-oncology kidney-cancer-oncology oncology prostate-cancer-oncology
Patient-derived xenografts models from prostate cancer (Hormone sensitive to CRPC)Download PDFoncology prostate-cancer-oncologyin-vivo
Orthotopic xenograft of Pc-3 human prostate cancer cellDownload PDFoncology prostate-cancer-oncologyin-vivo
Ectopic xenograft of Pc-3 human prostate cancer cellDownload PDFoncology prostate-cancer-oncologyin-vivo
HT29 human colon cancer cell orthotopic xenograftDownload PDFcolon-cancer-oncology oncologyin-vivo
Patient-derived xenografts models of kidney cancersDownload PDFkidney-cancer-oncology oncologyin-vivo
Organoids from bladder cancersDownload PDFbladder-cancer-oncology oncologyin-vitro
SKOV-3 xenograft model of human ovarian carcinomatosisDownload PDFoncology peritoneal-carcinomatosis-from-ovarian-cancerin-vivo
Patient-derived xenografts models of bladder cancersDownload PDFbladder-cancer-oncology oncologyin-vivo
AY27 rat bladder cancer cell orthotopic xenograftDownload PDFbladder-cancer-oncology oncologyin-vivo
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Evaluation of contraction or relaxation of isolated tissues (human or animal)Download PDFgynecologyin-vitro
Uterine contraction in late-pregnant ratDownload PDFgynecology preterm-birthin-vivo
Mouse preterm parturition modelsDownload PDFgynecology preterm-birthin-vivo
Ovariectomy-induced urinary dysfunction in miceDownload PDFgynecology menopause-induced-bladder-dysfunctionin-vivo
Uterotrophic BioassayDownload PDFgynecology testing-and-assessment-of-endocrine-disrupting-chemicalsin-vivo
Titlepathology_hfiltervivo-vitro_hfilter
Evaluation of contraction or relaxation of isolated tissues (human or animal)Download PDFandrologyin-vitro
Cavernous nerve injury-induced erectile dysfunctionDownload PDFandrology erectile-dysfunctionin-vivo
Erectile dysfunctionDownload PDFandrology erectile-dysfunctionin-vivo
Drug induced penile erectionDownload PDFandrology erectile-dysfunctionin-vivo
Chronic prostate hyperplasia and inflammation induced by sulpirideDownload PDFandrology benign-prostatic-hyperplasia-bph-andrologyin-vivo
Chronic pelvic pain and inflammation induced by carrageenanDownload PDFandrology prostatitis prostatitis-andrology urologyin-vivo
Titlepathology_hfiltervivo-vitro_hfilter
Colorectal Distension induced Allodynia in TNBS-treated ratsDownload PDFgastroenterology irritable-bowel-syndrome-ibs
Evaluation of contraction or relaxation of isolated tissues (human or animal)Download PDFgastroenterologyin-vitro
Gastrointestinal transit (fecal output)Download PDFgastroenterology transit-disordersin-vivo
Gastrointestinal transit (charcoal meal test)Download PDFgastroenterology transit-disordersin-vivo
Gastrointestinal transit (enteropooling)Download PDFgastroenterology transit-disordersin-vivo
Visceral pain induced by mustard oilDownload PDFgastroenterology irritable-bowel-syndrome-ibsin-vivo
Peritoneovisceral pain induced by acetic acidDownload PDFgastroenterology irritable-bowel-syndrome-ibsin-vivo
Chronic colitis induced by TNBSDownload PDFgastroenterology inflammatory-bowel-disease-ibdin-vivo
Chronic colitis induced by Dextran Sodium Sulfate (DSS)Download PDFgastroenterology inflammatory-bowel-disease-ibdin-vivo
Acute colitis induced by oxazoloneDownload PDFgastroenterology inflammatory-bowel-disease-ibdin-vivo
Acute colitis induced by TNBSDownload PDFgastroenterology inflammatory-bowel-disease-ibdin-vivo
Acute colitis induced by Dextran Sodium Sulfate (DSS)Download PDFgastroenterology inflammatory-bowel-disease-ibdin-vivo

Our Platform & Innovation

Urosphere’s experimental platform consists of both in vivo and in vitro pharmacological assays. We also provide access to a unique biobank of PDX preclinical models from urogenital cancers.

Finally, Urophere offers consultancy services for the preclinical development of your compounds.

Urosphere Platform

An optimized platform and a certified quality level for preclinical R&D services and innovation.

Urosphere Innovation

Development of customized models Codevelopment of therapeutic compounds Licensing.

Scientific

Publications

Scientific Publications

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Therapeutic Areas

Urology

Nephrology

Oncology

Gynecology

Andrology

Gastroenterology